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Objective:To investigate the clinical characteristics and influencing factors of pain symptoms in patients with idiopathic Parkinson′s disease.Methods:The King′s Parkinson′s Disease Pain Scale (KPPS) was used to evaluate pain of 106 patients with Parkinson′s disease. The Pittsburgh Sleep Quality Index (PSQI), the Fatigue Scale-14 (FS-14), the Unified Parkinson′s Disease Rating Scale Ⅲ, Hoehn-Yahr scale (H-Y), Mini-Mental State Examination (MMSE), Hamilton Anxiety Scale (HAMA) and Hamilton Depression Scale (HAMD) were used to assess the sleep status of patients, the degree of fatigue, motor function, severity of symptoms, cognitive function, anxiety and depression. Fifty-eight patients were followed up for three to six months.Results:The incidence of pain in Parkinson′s disease patients was 50.0% (53/106), of which skeletal muscle pain was the most common. Parkinson′s disease patients with a longer course of disease were more likely to have pain [course of disease in Parkinson′s disease with pain was 3.0 (1.5, 5.0) years, in Parkinson′s disease without pain was 2.0 (1.5, 2.5) years, Z=-2.0, P=0.046]. Male patients had more severe pain than female patients [KPPS scores in males were 14.5 (8.0, 21.5), in females were 10.0(4.0, 15.3), Z=-2.81, P=0.005]. In the first evaluation, the H-Y grading and the FS-14 scores of Parkinson′s disease patients with pain were significantly higher than those without pain [H-Y grading in Parkinson′s disease patients with pain was 2.0 (1.5, 2.5), in Parkinson′s disease patients without pain was 2.0 (1.5, 2.0), Z=-2.02, P=0.043; FS-14 scores in patients with pain were 10.0 (8.0, 11.0), in patients without pain was 8.0 (5.0, 10.0), Z=-3.32, P=0.001]. The KPPS scores were positively correlated with the scores of HAMA and HAMD ( r=0.39, P=0.005; r=0.38, P=0.007). Binary Logistic regression analysis showed that Parkinson′s disease patients with higher scores of FS-14 had an increased risk of developing pain ( OR=1.27, 95% CI: 1.09-1.48, P=0.002). The changes of KPPS scores were associated with the changes of PSQI and FS-14 scores ( r=0.54, P=0.002; r=0.50, P=0.003). The decrease of KPPS scores was only positively correlated with the decrease of FS-14 scores when the drug and medication status remained unchanged ( r=0.421, P=0.045). Multiple linear regression analysis showed that the decrease of FS-14 scores was associated with the decrease of the KPPS scores ( OR=2.02, P=0.033). Conclusions:Parkinson′s disease patients have a high incidence of pain, and fatigue is a factor for predicting the occurrence and outcome of pain in Parkinson′s disease. The severity and change of pain in Parkinson′s disease patients are related to anxiety, depression, sleep and fatigue, suggesting that there may be a common pathogenesis of pain, emotion, sleep and fatigue in Parkinson′s disease patients.
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@#AIM: To investigate the current situation of myopia among pupils in Baotou and analyze the factors related to myopia, so as to provide data support and theoretical basis for myopia prevention and control in education and health departments.<p>METHODS: A random cluster sampling method was adopted to investigate the vision situation of students aged 7-14 in 26 primary schools in the urban and pastoral areas of Baotou from January to November 2019, 2000 questionnaires on myopia-related factors were distributed, and 1630 valid questionnaires were finally formed, and a myopia database was established for statistical analysis. <p>RESULTS: There were 14 845 myopia among the 31 080 students surveyed, and the myopia rate was 47.8%(14845/31080). Among them, the myopia rate of boys was 44.3%(6912/15609), and that of girls was 51.3%(7933/15471). The myopia rate in urban areas was 50.4%(9310/18489)and in pastoral were as was 44.0%(5535/12591). The myopia rate of Han nationality was 48.0%(13185/27442), and of Mongolian nationality was 44.6%(1149/2576), the other ethnic groups was 48.1%(511/1062)(<i>P</i><0.05). The prevalence of myopia of 11, 12, 13,and 14-year-old urban pupils were: 51.9%(1333/2568), 62.8%(1671/2662), 72.0%(3415/4740), 45.4%(704/1551),and the pastoral areas of the same age group were 46.5%(938/2019), 58.0%(1089/1877), 68.3%(1557/2279), 36.2%(338/934). The myopia rate of urban pupils in 11-14 age group was higher than that in pastoral areas(<i>P</i><0.05). Among them, doing eye exercises and eating fruits and vegetables were protective factors. Area, grade, tummy reading, reading and writing under low light, or using electronic products, parents' myopia, and father's education were risk factors for myopia. <p>CONCLUSION: The prevalence of myopia in Baotou primary school students is at a relatively high level. With the increase of age, the prevalence of myopia increases. Many factors are related to myopia in primary school students. Parents and education departments should carry out relevant interventions.
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@#AIM: To understand the epidemic situation of retinopathy of prematurity in Sanya region and its related factors analysis so as to provide a reference for the prevention of the disease in this region.<p>METHODS: A total of 243 premature infants(486 eyes)with gestational age of less than 36 weeks and 35 cases of full moon(70 eyes)who were delivered in Sanya Maternal and Child Health Care Hospital from January to December 2019 were selected as the research objects. Fundus screening was performed. And the incidence of retinopathy of prematurity was calculated according to the diagnostic criteria, and univariate and multivariate Logistic regression analysis was performed on the related data of the mothers before and during pregnancy.<p>RESULTS: There was no retinopathy in the whole moon, but 36 cases of premature infants with retinopathy of prematurity. And the incidence of the disease was 14.8%(36/243). Among them, about half(58.3%)of the children with stage Ⅰ disease. Followed by stage Ⅱ disease(30.6%), stage Ⅲ disease(8.3%)and stage Ⅳ disease(2.8%), no stage Ⅴ disease were found. Meanwhile, 2 children with threshold lesions(5.6%). Except for the gestational age, there were no significant differences in the related factors of menstruation, gestational age, gestational births and pregnancy complications between full-term and normal preterm mothers(<i>P</i>>0.05), but compared with the mothers of premature infants, the differences were statistically significant(<i>P</i><0.05). The irregular menstruation, older pregnancy, gestational age short, polyembryony, eclampsia, PIH, diabetes and perinatal infection were independent risk factors for retinopathy of prematurity(<i>P</i><0.05).<p>CONCLUSION: The incidence of retinopathy of prematurity is high in Sanya, which should be paid great attention. At the same time, there are many influencing factors. It is an effective method to reduce retinopathy of prematurity in this area that menstrual conditioning before pregnancy, avoid advanced pregnancy, term birth, monocyesis and control pregnancy complications.
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【Objective】 To investigate the related factors of allogeneic blood transfusion (ALBT) in total hip arthroplasty. 【Methods】 Thebasic information, surgical details and laboratory data of 258 patients who underwent total hip arthroplasty in Orthopedics Department of our hospital were collectedfrom the electronic medical record system and laboratorytest system. The factors concerningALBT were obtainedby single factor and multivariate logistic regression analysis. 【Results】 The ALBT rate in this study was 19%, and the differencesin such important factors affecting ALBT as gender, age, intraoperative blood loss, drainage volume, operation duration, preoperative hemoglobin (Hb), preoperative activated partial thromboplastin time (APTT), preoperative prothrombin time (PT) andhypertension between the two groupswere notable (P<0.05). Multivariate regression analysisrevealed that the independent related factors ofALBT were age ≥ 60 years (OR3.577), intraoperative blood loss (OR1.003), drainage volume (OR1.004)and preoperative PT (OR1.888). Preoperative Hb (OR0.94) was a protective factor. 【Conclusion】 Specific and individualized evaluation of ALBT, aimed atreducingunnecessary blood transfusion, can be provided through the analysis of relevant factors.
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Objective:To investigate the distribution of traditional Chinese medicine (TCM) syndromes in patients with coronary heart disease (CHD) in 6 months after interventional therapy, and to analyze relevant influencing factors. Method:The clinical data of 1 000 patients with coronary heart disease in 6 months after interventional therapy, including the four diagnosis information of TCM, were collected, and the distribution of TCM syndromes and the influencing factors were analyzed. Result:Among 48 kinds of information about the four diagnostic methods of TCM, chest pain was the most frequent (98.10%)， among 9 kinds of common TCM syndrome types, blood stasis was the most frequent (89.90%), and the others were heart-Qi deficiency syndrome, phlegm turbidity syndrome, cold-dampness syndrome, kidney-Qi deficiency syndrome, heart-Yin deficiency syndrome, kidney-Yin deficiency syndrome, Heart-Yang deficiency syndrome and kidney-Yang deficiency syndrome in turn. Among 6 common TCM syndrome types, Qi deficiency and blood stasis syndrome were the most frequent (35.40%), and the others were phlegm turbidity and blood stasis syndrome, cold congealing heart pulse syndrome, Qi-Yin deficiency syndrome, heart-kidney Yin deficiency syndrome and heart-kidney-Yang deficiency syndrome in turn. There was no significant difference in sex ratio among different syndrome types . Patients with heart-kidney Yang deficiency syndrome had no significant difference. Compared with the average age of other syndromes, there were significant differences. Common complications included hypertension, diabetes, cerebrovascular diseases and dyslipidemia, among which hypertension had the highest frequency, with significant differences from other diseases (P<0.05). Phlegm, turbidity and blood stasis were found in patients with hypertension. The risk of syndromes was higher (OR=3.29, 95% CI [2.11, 5.05]), while the risk of cold congealing heart pulse syndrome was lower (OR=0.56, 95% CI [0.32, 0.98]), the risk of Qi and Yin deficiency was higher (OR=2.88, 95% CI [2.01, 4.99]), whereas the risk of heart and kidney Yang deficiency was lower (OR=0.54, 95% CI [0.29, 0.95]) when complicated with cerebrovascular diseases. The risk of Qi deficiency and blood stasis was higher (OR=2.97, 95% CI [2.05, 5.28]), while the risk of heart and kidney Yang deficiency was lower (OR=0.54, 95% CI [0.29, 0.95])， the risk of phlegm turbidity and blood stasis was higher when complicated with dyslipidemia (OR=3.55, 95% CI [2.32, 5.29]), and the risk of heart and kidney Yang deficiency was lower (OR=0.54, 95% CI [0.29, 0.95]). The time distribution of the disease had obvious seasonal characteristics. Conclusion:The main distribution characteristics of TCM syndromes in 6 months after coronary heart disease intervention are basically the same as those in patients without intervention. The main TCM syndromes are Qi deficiency and blood stasis syndrome, phlegm turbidity and blood stasis syndrome, cold congealing heart pulse syndrome, Qi-Yin deficiency syndrome, heart-kidney Yin deficiency syndrome and heart-kidney-Yang deficiency syndrome. The distribution pattern may be related to age, complications and seasons.
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Objective To investigate the relevant factors of type 2 diabetes mellitus (T2DM) with cerebral infarction (CI).Methods A total of 323 patients with T2DM from February 2012 to March 2017 in Inner Mongolia medical university affiliated hospital were included in this study.150 patients with T2DM and CI were considered as experiment group,173 cases of T2DM without CI were considered as control group.The clinical data of two groups were analyzed.Results The history of diabetes,smoking and hypertension were longer in experiment group than in control group (P＜ 0.05).The patients in experiment group had higher fasting blood glucose (FBG),glycosylated hemoglobin (HbA1c),total triglycerides (TG),total cholesterol (TC),low-density lipoprotein cholesterol (LDL-C),non-HDL-C,homocysteine (Hcy),fibrinogen (FIB),retinol binding protein 4 (RBP4) and lower HDL-C,apolipoprotein A1 (ApoA1) than the patients in control group (P＜ 0.05).Multiple-factor logistic regression analysis showed that long-term smoking,long history of hypertension,high TG,high LDL-C,high non-HDL-C,high Hcy,high RBP4,low HDL-C and low ApoA1 were risk factors for CI in patients with T2DM (P＜0.05).After adjusting common variables (diabetes history,hypertension history,smoking history,HbA1c,TG,TC),multiple-factor logistic regression analysis showed that LDL-C,non-HDL-C,Hcy,RBP4 were risk factors for CI in T2DM (P＜0.05).HDL-C and ApoA1 were protective factors for CI in T2DM (P＜0.05).Conclusion The risk factors for CI in patients with T2DM include long-term smoking,long hypertension history,high HbA1c,high TG,high LDL-C,high non-HDL-C,high Hcy,high RBP4,low HDL-C and low ApoA1.Patients should be advised to quit smoking,control blood glucose and blood pressure,and regulate blood lipid levels.
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Progression of acute isolated pontine infarction (IPI) is a common clinical event that positively correlates with the patients' adverse prognosis.Therefore,exploration on the relevant factors and predictors to the progression of IPI has become the current research hotspot.To date,the relevant factors that have been proposed include basilar artery branch disease,female,hypertension and blood pressure fluctuation,hyperglycemia,morphological features of the lesions (ventral surface of pons involvement,located at the lower pons,multiple axial slices affected,conglomerated beads shape),severe white matter diseases,atherosclerosis,long diameter and midline location of basilar artery,and so on.However,the interpretation on existing results has to be cautious as the definition for progressive IPI,criteria for inclusion and exclusion,and examinations are inconsistent in different studies.The investigation on relevant factors to the progression of IPI still requires standardized,large-scale prospective clinical studies.
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Objective: To evaluate factors that affect recurrence ofⅠb-Ⅱa cervical cancer after surgery or radiation therapy, and to provide evidence for prevention and personalized treatment of cervical cancer recurrence. Methods: We retrospectively analyzed clini-cal and pathological data of 193 patients with stageⅠb-Ⅱa cervical cancer who were diagnosed and treated in Affiliated Cancer Hos-pital of Xinjiang Medical University from January 2010 to April 2015. The patients were assigned into the following two groups: postop-erative radiotherapy recurrence group (36 cases) and non-recurrence group (157 cases). Factors related to recurrence after postopera-tive radiotherapy were analyzed. Results: The incidence rates of squamous cell carcinoma, adenocarcinoma, and other cervical cancer types were 90.2% (174/193), 5.7% (11/193), and 4.1% (8/193), respectively. The recurrence rates of squamous cell carcinoma, adeno-carcinoma, and other cervical cancer types were 16.7% (29/174), 45.5% (5/11), and 25.0% (2/8), respectively. The difference was statis-tically significant (χ2=12.463, P<0.05). The proportion of patients with age≤40 years, adenocarcinoma, vaginal margin, vascular inva-sion, lymph node metastasis, and parametrial invasion was higher in the relapse group than in the non-relapse group; the difference was statistically significant between the two groups (P<0.05). The odds ratio (OR) values for positive vaginal margin, positive vascular invasion, and positive parametrial invasion were above 1 (P<0.05). Therefore, these three factors were independent risk factors for cer-vical cancer recurrence after radiotherapy. Conclusions: Among stage Ib-IIa cervical cancer cases, squamous cell carcinoma had the highest recurrent incidence. However, the rate of recurrence after surgery or radiation therapy was the highest for adenocarcinoma. Postoperative pathology suggests that patients with positive vaginal margins, positive vascular infiltration, and positive parametrial in-vasion have a high risk of recurrence after radiotherapy and should be followed-up carefully.
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@#AIM: To investigate the incidence of amblyopia in preschool children and correlation factors in Bao'an District of Shenzhen so that to provide possible basis for the prevention of regional amblyopia. <p>METHODS: Totally 818 preschoolers with visual acuity screening were selected and studied from June 2017 to February 2018 in our Hospital. The incidence of amblyopia in children was recorded with the amblyopia diagnostic criteria and they were treated as observation groups. The others were treated as controls. The single factor and multivariate Logistic regression analysis were performed for the two groups. <p>RESULTS:The incidence of amblyopia in preschool children in Bao'an District of Shenzhen was 5.7%(47/818). Among them, ametropic amblyopia was the most common(63.8%), the second was anisometropic amblyopia(21.3%), the third was strabismic amblyopia(12.8%)and in the end was form deprivation amblyopia(2.1%). By single factor analysis: there were statistically significant differences between two groups for the correlation factors of gestational age, gravidity and parity history, gestational weeks and nearsightedness(amblyopia)family history(<i>P</i><0.05). By multivariate Logistic regression analysis: the older gestational age, more gravidity and parity, shorter gestational weeks and positive nearsightedness(amblyopia)family history were the highest risk factor for children with amblyopia(<i>P</i><0.05). <p>CONCLUSION: The incidence of amblyopia in preschool children in Bao'an District of Shenzhen is high and it should be taken seriously. In the meantime, there are many influencing factors. But comprehensive preschool vision screening is an effective method for early discovery, early diagnosis and early treatment.
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Objective To investigate the influence of hyperbaric oxygen (HBO) on blood pressure and heart rate in adult patients with cervical spinal cord injury (SCI) and its related factors. Methods From May 2015 to October 2017, 101 cases of adult cervical spinal cord injury in our department were select-ed as observation group, who were divided into four subgroups (AIS A~D) respectively, according to the ASIA score. Other 101 cases of sudden hearing loss without spinal cord injury were selected as control group, who were divided into four subgroups with gender and age matched with four subgroups of the observation group, re-spectively. Blood pressure and heart rate were measured before the compression, at the end of the compression, 30 minutes after oxygen taken in, before the decompression and at the end of the decompression; and were com-pared between groups. The fluctuations of blood pressure and heart rate were correlated and regression analyzed with age, course and AISA score respectively. Results In ASI A~C, the blood pressure fluctuated obviously during the course of hyperbaric oxygen therapy in the ob-servation group (P<0.05). There was no significant difference in blood pressure between ASI D of the observa-tion group and their controls (P>0.05). Lower extremity motor score of ASIA was correlated with the fluctuation of blood pressure (P<0.05). Conclusion The blood pressure fluctuates in patients with cervical spinal cord injury (AIS A~C) during hyperbaric oxy-gen, which should be paid attention to. Lower extremity motor score of ASIA is an independent factor affecting blood pressure. The higher the lower extremity motor score, the smaller the blood pressure fluctuation.
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Objective To analyze the influence factors for complete embolization of intracranial aneurysms. Methods The clinical data of 546 inpatients with single intracranial aneurysm underwent interventional embolization at the Department of Neurosurgery,Anhui Provincial Hospital Affiliated to Anhui Medical University from January 2013 to January 2017 were analyzed retrospectively. They were divided into either a complete embolization group (n=255) or a incomplete embolization group (n=291) according to the immediate embolism degree of aneurysms. Single factor,multiple factors logistic regression analyses were used to analyze the factors associated with complete embolization of intracranial aneurysms. Results Univariate analysis showed that there were significant differences in the rupture status,anatomical morphology,Hunt-Hess grade, aneurysm size and neck width, different treatment regimens, and aneurysm angle between the patients in the complete embolism group and the incomplete embolism group ( all P<0. 05). The results of multivariate regression analysis showed that aneurysm size ( OR,0. 344,95%CI 0. 204-0. 578,P<0. 01),aneurysm rupture status (OR,0. 568,95%CI 0. 314-0. 947,P=0. 030), embolism ways (OR,3. 699,95%CI 2. 223-6. 153,P<0. 01),neck width of aneurysm (OR,0. 326, 95%CI 0. 198-0. 539,P=0. 003),aneurysm angle (OR,0. 647,95%CI 0. 451-0. 928,P=0. 018),and aneurysm morphology (OR,1. 689,95%CI 1. 118-2. 552,P =0. 013) were the independent factors of affecting the complete embolization of intracranial aneurysms. Conclusion Tiny, unruptured, narrow-neck, small inclination angle,regular-shaped aneurysms,stent-assisted or balloon-assisted embolization of intracranial aneurysms are easier to embolize the aneurysms completely.
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Objective To analyze the influence factors for complete embolization of intracranial aneurysms. Methods The clinical data of 546 inpatients with single intracranial aneurysm underwent interventional embolization at the Department of Neurosurgery,Anhui Provincial Hospital Affiliated to Anhui Medical University from January 2013 to January 2017 were analyzed retrospectively. They were divided into either a complete embolization group (n=255) or a incomplete embolization group (n=291) according to the immediate embolism degree of aneurysms. Single factor,multiple factors logistic regression analyses were used to analyze the factors associated with complete embolization of intracranial aneurysms. Results Univariate analysis showed that there were significant differences in the rupture status,anatomical morphology,Hunt-Hess grade, aneurysm size and neck width, different treatment regimens, and aneurysm angle between the patients in the complete embolism group and the incomplete embolism group ( all P<0. 05). The results of multivariate regression analysis showed that aneurysm size ( OR,0. 344,95%CI 0. 204-0. 578,P<0. 01),aneurysm rupture status (OR,0. 568,95%CI 0. 314-0. 947,P=0. 030), embolism ways (OR,3. 699,95%CI 2. 223-6. 153,P<0. 01),neck width of aneurysm (OR,0. 326, 95%CI 0. 198-0. 539,P=0. 003),aneurysm angle (OR,0. 647,95%CI 0. 451-0. 928,P=0. 018),and aneurysm morphology (OR,1. 689,95%CI 1. 118-2. 552,P =0. 013) were the independent factors of affecting the complete embolization of intracranial aneurysms. Conclusion Tiny, unruptured, narrow-neck, small inclination angle,regular-shaped aneurysms,stent-assisted or balloon-assisted embolization of intracranial aneurysms are easier to embolize the aneurysms completely.
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Objective To collect the incidence and distribution of congenital malformations ,find monitor-ing and preventive measures,to provide a basis for reasonable allocation of health resources for clinical depart-ments. Methods According to The International Classification of Diseases(ICD-10)chapter 17 encoding table, we analyze our hospital′s cases from January 2003 to December 2010 in order to understand the incidence of con-genital malformations of every system. Results Top five diseases are:cleft palate deformity ,genital malforma-tion,congenital heart disease and digestive system malformation in equal third place,and facial deformity. The age ranged from 1d to 35 y,men more than women. Conclusions The key to effectively reduce the incidence of con-genital malformation is strictly implement the three-level intervention mechanism. Prevention ,early detection and early treatment will improve the patient′s quality of life.
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Objective To analyze the relevant factors of vaginal delivery postpartum hemorrhage,and discussion how to prevent postpartum hemorrhage.Methods 2 417 maternal women who hospitalized vaginal delivery were selected.Preeclampsia,macrosomia,placental abruption,obesity,premature rupture of membranes,high blood pressure,gestational age,maternal age,maternal time,the number of abortion,scar uterus vaginal delivery,oxytocin induced labor,misoprostol for cervical mature,forceps midwifery,and the correlation of postpartum hemorrhage were analyzed.Results The incidence rate of postpartum hemorrhage was 15.22%.Pre -eciampsia,macrosomia,placental abruption had significant association with postpartum hemorrhage(χ2 =26.75,0.16,22.26,all P 0.05 ).Oxytocin induced labor,misoprostol for cervical mature,forceps midwifery were significantly associated with postpartum hemorrhage(χ2 =45.66,21.77,88.06,all P <0.01 ).Conclusion Prenatal maternal and neonatal weight control,prevention of preeclampsia,placental abruption occurred to prevent postpartum hemorrhage;Intrapartum avoid no indications oxytocin,misoprostol for cervical mature,forceps midwifery and reduce postpartum hemorrhage;Postpartum accurately estimated blood loss, active treatment,avoid serious complications.
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Objective: To explore the relevant factors of acquired swallowing disorders in adult patients after cardiac surgery. Methods: A Jiatian water swallowing screening test was conducted for adult patients after cardiac surgery in our hospital from 2015-03 to 2015-09. There were 32 patients with acquired swallowing disorder deifned as Case group and meanwhile 420 patients without swallowing disorder at the same word deifned as Control group. Non-conditional Logistic regression analysis was applied to study the relevant factors for acquired swallowing disorders. Results: The overall incidence of acquired swallowing disorders was 7.08%. Multi Logistic regression analysis presented that duration of endotracheal intubation (OR=1.060,P<0.001), pre-operative arrhythmia (OR=2.780,P=0.019), NYHA grade (OR=1.789, P=0.033) and Euroscore (OR=1.216,P=0.040) were the relevant factors for the occurrence of acquired swallowing disorders in adult patients after cardiac surgery. Conclusion: Medical professionals should pay special attention to patients with above mentioned risk features at post-operative drinking to reduce the complications of acquired swallowing disorders.
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Objective To explore current situation of hospital outpatient injection room infection and to discusse relevant countermeasures of infection control .Methods A retrospective analysis was conducted in 245 patients admitted and got infected in our hospital outpatient department injection room from October 2012‐to October 2013 .By analyzing its infection type ,treatment time ,age ,etc .,and in winter and items ,air ,medical staff hand in spring and summer and fall of hospital respectively we understand the hospital infection and the seasonal relationship ,the related factors of hospital infection ,and develop targeted and effective inter‐vention measures .Results The outpatient injection room infection were mainly occurred in respiratory system and digestive sys‐tem ,the occurrence rates were 54 .29% (133/245) ,25 .31% (62/245) ,respectively .The infection rate of treatment time> 7 d (2 .74% ) apparently higher than < 7 d (1 .09% ) (χ2 = 56 .246 ,P= 0 .000) .The infection rate of people whose age over 40 (1 .91% )apparently higher than age < 40 (1 .13% ) (χ2 = 12 .316 ,P= 0 .000) .The qualified rate of atmosphere in Winter and Spring (68 .46% ) was significantly lower than summer and autumn (89 .23% ) (P<0 .05) ,the qualified rates of surfaces and hands of medical staffs (84 .62% ,82 .31% ) were significantly higher than summer and autumn(63 .08% ,66 .15% ) .Conclusion The out‐patient injection room infections were related to a variety of factors ,we could carry on the comprehensive analysis and formulate specific interventions to reduce hospital infection .
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Objective To identify the relevant factors for the loculation clinically in children with parapneumonic pleural effusion (PPE).Methods The clinical data of 172 children with PPE were retrospectively reviewed from January 2012 to March 2015 in Children's Hospital of Hebei Province.Based on the findings of chest ultrasound, the subjects were divided into 2 groups, the loculation group (78 cases) and the control group (94 cases).The comparison was made between the 2 groups in gender, age, course of disease and fever before admitting into hospital, the location of the effusion, white blood cells (WBC) and the percentage of neutrophils (N), blood platelet (PLT) ,lactate dehydrogenase (LDH),C-reactive protein (CRP), mycoplasma (MP), the routine and biochemical examination of pleural fluid, including white cell count (WBCp), the percentage of polymorphonuclear cell (PMN), lactate dehydrogenase (LDHp) ,glucose (GLU) ,adenosine deaminase (ADA) ,lactic acid (LAC) and C-reactive protein (CRPp).If the result of single factor regression showed P ＜ 0.01, the indicators were analyzed by the multifactor Logistic regression.The receiver operator characteristic (ROC) curve was drawn to evaluate the prediction ability of Logistic regression models.Results (1) The result of single factor regression indicated that the risk factors included age, WBC, PLT, LDH, MP, WBCp, PMN, GLU and LAC (all P ＜ 0.05).(2) The result of multifactor Logistic regression showed that the factors included PLT (OR =3.437,P =0.007), LDH (OR =0.306, P =0.006), GLU (OR =0.324, P =0.037), MP (OR =0.375 ,P =0.022) and LAC (OR =3.656, P =0.003).(3) The area under the ROC curve was 0.876, P =0.000,which indicated that the regression models had over medium diagnostic accuracy.Conclusions When PLT ＞ 434.5 × 109/L,LDH ＜400 U/L,non MP infection,GLU ＜6.11 mmol/L and LAC ＞3.83 mmol/L,it may indicate that the formation of loculation for the PPE children.
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Objective To analyze the related factors regarding diabetic nephropathy (DN).Methods A total number of 756 diabetic patients from 2009 to 2011 were analyzed retrospectively.Three groups were formed according to the urinary albumin excretion rates (UAER).Patients with UAER＜20 μg/min was grouped to group A,with UAER from 20 to 200 μg/min as group B,and the others with UAER ≥200 μg/min was grouped to group C.General characteristics and laboratory parameters were then compared and related factors of DN analyzed.Results The constituent ratio of nephropathy was 30.2％ (228/756).Patient's age,duration of disease,both diastolic and systolic blood pressure of group A were significantly higher than the non-DN group (A) (P＜0.05).Patient's age,disease duration,both diastolic and systolic blood pressure of group C were (64.08± 11.71)years,(14.67± 7.34)years,(87.43 ± 14.36)mm Hg,(152.45 ± 18.48)mm Hg,respectively,with statistically significant difference (P＜0.05) between group C and group B.FPG,TG,TC,HDL-C,UA,HbAlc,FINS,FCP of group B were (9.27 ± 3.06) mmol/L,(1.98 ± 0.37) mmol/L,(5.01 ± 1.08) mmol/L,(1.05 ± 0.35) mmol/L,(312.78 ± 39.83) mmol/L,(9.33 ± 1.47)％,(11.45 ± 7.83) μU/ml,(509.73 ±132.78) pmol/L respectively,with significant difference (P＜0.05) between group B and group A.FPG,TG,HDL-C,UA,FINS,FCP of group C were (9.29 ± 3.12)mmol/L,(2.02 ± 0.36)mmol/L,(1.04 ± 0.27) mmol/L,(389.72 ± 46.32) mmol/L,(11.09 ± 8.29) μ U/ml,(575.77 ± 143.29) pmol/Lrespectively,with significant difference (P＜0.05) between group C and group A.UA,FINS,FCP were found with significant differences (P＜0.05) between group C and group B.Data from multivariate logistic regression showed that DNs were related with disease duration,BMI,systolic blood pressure,HbAlc,FPG,UA.Conclusion DN was closely related to the duration,age,blood sugar,blood lipids,blood pressure,uric acid levels of the disease.
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Objective To investigate the patients with postoperative skin damage around the stoma after Miles operation,take measures according to the influencing factors,and explore an effective way to reduce the incidence of skin damage around the stoma patients.Methods There were 62 cases of skin damage around the stoma in 110 cases of patients with permanent colostomy in out-patient follow-up.Each patient with skin damage occurring around the stoma were retrospectively analyzed the reasons,and the related factors that might affect Miles postoperative stoma skin damage were analyzed.Results The incidence rate of Miles postoperative skin damage around the stoma was 56.36％,through the multi-factor Logistic regression analysis,there were six related factors with the Miles postoperative skin damage around the stoma,patients' excrement stimulation,ostomy bag allergies,improper operation of the replacement of the ostomy bag,the potential skin disease,excessive scrub / rub the skin,unfamiliar with ostomy care knowledge were the influencing factors of patients with skin damage around the stoma.Conclusions Appropriate stoma care products and paste methods,detailed guiding of patients and their families about ostomy care knowledge and skills can significantly reduce the incidence rate of Miles postoperative skin damage around the stoma.
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Objective To investigate the clinical features,etiology and related clinical factors in neonatal anemia.Methods Two hundreds and sixty four infants admitted to the Neonatal Intensive Care Unit between January 2009 to March 2012 were retrospectively analysed with different levels,different age,different gestational age.Results Among 264 patients,the occupancy of blood loss anemia was 54.5 ％.Mild and medium neonatal anemia were more than severe anemia (172 vs 92).Fetomaternal hemorrhage syndrome occurred commonly in severe anemia (16.3％,15/92).Early anemia was more than late anemia(182 vs 82).Hemorrhagic anemia in early anemia (64.3％,117/82)occurred mainly.Late anemia with infection mainly (67.1％,55/82).Fetomaternal hemorrhage syndrome were all early anemia and term to account for a higher proportion (94.4％,17/18);twin-to-twin transfusion syndrome occurred commonly among preterm term infants (96.7％,29/30).Conclusion Blood loss anemia was the main etiological factor resulting in neonatal anemia.The incidence of mild and medium neonatal anemia was quite high.Early anemia was more than late anemia.There might be some differences in the etiology between term and perterm infants.